A rapid diagnostic test uncut sheet is an analysis of a sample for the purposes of determining the specific medical condition or disease associated with the sample. A medical condition typically is diagnosed through a physical examination, such as x-rays, blood tests, and other methods. A sample is taken from the body and examined under a microscope in order to identify and measure the composition of the sample. The sample is then submitted to a laboratory in order to undergo a rapid diagnostic test, or RDT. If the results from the lab are abnormal, then further analysis and research will need to be conducted in order to find out the underlying cause of the problem.
For many diagnostic tests, the sample is evaluated using both X-rays and/or blood samples. However, for rapid tests, a sample is only required once. An example of an RDT that only requires a sample once is the gas chromatography method. For this method, a sample of the gas produced from a reaction between two chemicals is needed. In order to evaluate the sample, a chemical process known as gas chromatography is used.
In most cases, there is no need to actually write down what has been measured. The results of a rapid test will already have been written into the machine’s database. The information entered will also already be formatted to make it easier for the user to read. On uncut sheets, the data that is being entered will have been typed. The user will simply need to type in a number and a title in order to generate a report from the results.
One of the advantages to uncut sheets is that the process for evaluation relies solely on the human eye. There is no need to correlate what is visible with what is measurable. For example, if a technician is evaluating a specimen and sees redness in a particular area of the specimen, he does not need to consult a laboratory and then translate this into measurements. He simply notes it on the uncut sheet and moves on to continue his work. The same can be said for any type of qualitative test, whether it is a qualitative analysis of a material or an immunological test that tests for antibodies.
When a sample is submitted to a laboratory for a rapid test, the DNA or qPCR test is usually performed first. This tests the genetic material of the bacteria on the surface of the material. Because this test can give false results if something else is present on the material (such as contamination), it is usually performed at a rapid testing laboratory that specializes in DNA and qPCR amplification and analysis. In cases of anthrax, a sample is usually submitted to a biochemistry laboratory that specializes in immunochromatographic assays for detection of antigens.
A second kind of rapid diagnostic test is the immunochromatographic assay. It is used to detect antibodies that target the bacteria, fungi, and viruses that cause disease. For example, if you test someone for chlamydia, you may use an immunochromatographic assay to detect antibodies that bind to the chlamydia protein.
A third kind of rapid test is the quantitative polymerase chain reaction (Roche). To perform this kind of test, a sample of material, usually cotton wool, is mixed with the enzyme that changes its structure. After it is mixed, the sample is exposed to the enzyme and then to a variety of different chemicals and antibodies. The color of the mixture changes as the various chemicals and antibodies attack the molecules on the uncut sheet. Because the material is usually in suspension, the color changes are easier to detect than if the material was in its gel form.
The last type of rapid diagnostic test to look for is a lateral flow rapid test. This product name is used to describe a patented, semi-automated fluid assay that detects infection by a type of bacteria called Haemoglobin. Infection can be detected if the product mixes antigens with a degranulation agent. Because the product has no reference to brand name, however, there is no way to tell whether it is good or not from the label.